Upstream Bio (UPB) Technical Analysis

As of 2026-07-22, UPB last traded at 6.59 USD (-5.59% on the day) and is in a downtrend on the daily timeframe — price below falling 50-DMA, 50-DMA below 200-DMA. Nearest levels: 5.85 USD support below, 8 USD resistance above. 14-day RSI is 36.6 (bearish).

Last updated 2026-07-22 · Source: FMP end-of-day prices (adjusted); indicators computed by SniperIQ

Is UPB in an uptrend or downtrend?

Upstream Bio is in a downtrend — price below falling 50-DMA, 50-DMA below 200-DMA.

Last close6.59 USD (-5.59%)
20-day average7.158 USD
50-day average7.395 USD
200-day average16.413 USD

Key support and resistance levels for UPB

Derived from swing pivots over the last 200 sessions:

LevelTypeStrengthTouches
8 USDResistanceStrong3
8.64 USDResistanceMinor1
9.6 USDResistanceMinor1
LevelTypeStrengthTouches
5.85 USDSupportMinor1

UPB 52-week range, momentum and volatility

52-week high33.68 USD (80.4% below)
52-week low5.85 USD (12.6% above)
14-day RSI36.6 (Bearish)
14-day ATR0.419 USD (6.35% of price, High volatility)

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Frequently asked questions

Is Upstream Bio (UPB) in an uptrend or downtrend?

As of 2026-07-22, UPB is in a downtrend on the daily timeframe — price below falling 50-DMA, 50-DMA below 200-DMA. Last close 6.59 USD vs 50-day average 7.395 USD and 200-day average 16.413 USD.

What are the key support and resistance levels for UPB?

Nearest support is around 5.85 USD (minor, 1 touch). Nearest resistance is around 8 USD (strong). Levels are derived from swing pivots over the last ~200 sessions.

What is UPB's 52-week high and low?

Over the last 52 weeks, UPB traded between 5.85 USD and 33.68 USD. It is currently 80.4% below its 52-week high.

Is UPB overbought or oversold?

The 14-day RSI is 36.6 — in a neutral 30–70 range. Momentum reads as bearish.

How volatile is UPB?

Its 14-day Average True Range is 0.419 (6.35% of price) — high volatility relative to price.